Lot 32 of 222:
Rare author offprint on DNA by Gamow  

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Lot closed - Sold For (Includes Buyer's Premium):$4,500
$1,000 - $1,500

“Possible Relation between DNA and Protein Structure” - rare author offprint

Gamow, George


Printed by Fisher, Knight & Co.



Single sheet, printed on both sides, with illustration. 21.8x13.8 cm (8½x5½"). [offered with]: Gamow. “Possible mathematical Relation of DNA and Proteins”. Journal Issue.  Presentation copy, inscribed "Geo [arrow] Jack" on front wrapper. 13 pp. Illustrated. 23.3x15 cm (9¼x6"), printed wrappers. Copenhagen: Ejnar Munksaard, 1953. 

Important and early DNA offprint from Nature Vol. 173, p.318, February 13, 1954, in which Gamow answered one of the pressing questions of the time among genetic researchers following Crick and Watson's announcement of DNA structure, "How does DNA code proteins?). In this paper, Gamow made the first serious attempt to answer the question: “Gamow attempted to solve the problem of how the order of the four different kinds of bases… in DNA chains could control the synthesis of proteins from amino acids. Crick has said that Gamow’s suggestions helped him in his own thinking about the problem... Gamow suggested that the… 20 combinations with repetition of four DNA bases taken three at a time correspond to the twenty amino acids that form proteins. This led Crick and Watson to enumerate the twenty amino acids common to proteins. Gamow’s contribution to solving the problem of genetic coding gave rise to important models of biological degeneracy.” At the end of the offprint, Gamow states "The detailed account of the proposed theory will appear in Kong. Dan. Vod Selsk," which is the accompanying journal. Very rare.

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Fine condition.

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