[16], 541, [23] pp. Title page printed in red & black, with engraved vignette. (sm. 4to) period calf, spine tooled in gilt, raised bands, morocco lettering piece, marbled endpapers.
The greatest Renaissance classic on prognosis, of which Boerhaave writes in his preface: "The first time I read this valuable production of Prosper Alpinus, I concluded, that there was nowhere to be found, a book fitter for promoting medicinal knowledge, and consequently none more worthy to be warmly recommended to students in medicine." Garrison-Morton 2194, citing the first edition of 1601. Blake, p. 12. Wellcome II, p. 36.