One page, 4to. In full: “I am sensible of the Marquess of Salisbury’s situation in having immediately acquainted me of the death of Mr. Devaines one of my Apothecaries. I as well as every one of my Predecessors have employed constantly Mr. Brandi’s shop, I desire therefore that Mr. Brandi Junior who is an Englishman may be appointed to succeed Mr. Devaines, the other Apothicary is now an old man, his employment is lucrative, the attention shown me by Mr. Battiscombe of Windsor during my illness, and his constant attendance when I am there will make him highly deserving of it when it shall become warrant.” At the time of the writing of this letter, George III was increasingly incapacitated by his illness, sometimes identified as porphyry, that caused blindness and senility. His recurring bouts of insanity became a political problem and ultimately caused him to submit to the establishment of a Regency in 1811.