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Signed and inscribed on front wrapper by Ebenezer Alden - a descendant of Mayflower passengers John and Priscilla Alden - and on the title page by Eben. Alden's granddaughter, Louisa Alden Sprague. Dr. Ebenezer Alden, Jr. (1788-1881) was in the seventh generation descended from John Alden of the Mayflower. He entered Harvard University in 1804 and graduated in 1808. He went on to study medicine at Dartmouth and at the University of Pennsylvania where he received his MD degree in 1811. He served as a military surgeon from 1812 to 1821 when he was discharged and began his private practice in Randolph Mass. - continuing until his death in 1881. Alden's inscription reads: This version was used in the Congregation at Cambridge while I was a member of College - and last under the ministry of Rev. Dr. Holmes in 1808." A compelling association for this early American imprint. Evans 11990.